The Relationship Between COVID-19 History and Arterial Vascular Elasticity Measured Using Accelerated Photoplethysmograph Analyzer in Medical Students

Authors

  • Tasya Zuhriya Putri Faculty of Medicine, Universitas Pembangunan Nasional Veteran Jakarta, Indonesia
  • Nurfitri Bustamam Faculty of Medicine, Universitas Pembangunan Nasional Veteran Jakarta, Indonesia
  • Tri Faranita Faculty of Medicine, Universitas Pembangunan Nasional Veteran Jakarta, Indonesia
  • Agneta Irmarahayu Faculty of Medicine, Universitas Pembangunan Nasional Veteran Jakarta, Indonesia

Keywords:

arteries, COVID-19, vascular elasticity, students

Abstract

Introduction: COVID-19 is a global health issue that can affect the cardiovascular system at various levels and cause damage to the endothelium, leading to decreased arterial elasticity and vascular dysfunction. This study investigates the relationship between COVID-19 history and arterial vascular elasticity in medical students. Methods: This study used a case-control design and a purposive random sampling technique. Data on COVID-19 history and characteristics of the subjects were collected using questionnaires, while arterial vascular elasticity was measured using the accelerated photoplethysmograph (APG) analyzer, SA-3000P. The sample consisted of 24 COVID-19 survivors (case) and 24 subjects without COVID-19 history (control). Results: This study found that three subjects (6.25%) had optimal arterial vascular elasticity, 28 subjects (58.3%) had normal elasticity, and 17 subjects (35.45%) had sub-optimal elasticity. No significant differences were found in age, gender, physical activity, dietary habits, body mass index, and family history of hypertension, diabetes mellitus, heart disease, and obesity between the case and control groups (p > 0.05). The Chi-square test results showed a significant relationship between COVID-19 history and arterial vascular elasticity (p = 0.003; OR = 9.8; CI = 2.2-42.0). Conclusion: COVID-19 survivors are nine times more likely to have sub-optimal arterial vascular elasticity compared to those who have not been infected with the virus. COVID-19 survivors are advised to adopt healthy lifestyles and undergo regular check-ups to mitigate the risk of developing vascular diseases.

References

Infeksi Emerging Kementerian Kesehatan RI. (2023). Kemkes.go.id. https://infeksiemerging.kemkes.go.id/dashboard/covid-19

Bruno RM, Spronck B, Hametner B, Hughes A, Lacolley P, Mayer CC, Muiesan ML, Rajkumar C, Terentes-Printzios D, Weber T, Hansen TW, Boutouyrie P. Covid-19 effects on arterial stiffness and vascular aging: Cartesian study rationale and protocol. Artery Research. 2021;27(2):59–68. https://doi.org/10.2991/ARTRES.K.201124.001

Zanoli L, Gaudio A, Mikhailidis DP, et al. Vascular dysfunction of COVID-19 is partially reverted in the long-term. 2023. https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.320460

Estabragh, Cooper JA, Salih A, Raman B, et al. Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank. Heart. 2022;109(2): 119–26. https://doi.org/10.1136/heartjnl-2022-321492

Castaneda D. A review on wearable photoplethysmography sensors and their potential future applications in health care. Int J Biosensors Bioelectronics. 2018;4(4). https://doi.org/10.15406/ijbsbe.2018.04.00125

Setiati S. Buku Ajar Ilmu Penyakit Dalam FK UI. Edisi VI. Jakarta: InternaPublishing; 2015.

Sherwood L. Fisiologi manusia dari sel ke sistem. Ed 9. Jakarta: EGC; 2018:

Anthony L Mescher. Histologi dasar junqueira. Jakarta: EGC; 2017.

Bruno RM, Nilsson P M, Engström G, Wadström BN, Empana JP, Boutouyrie P, Laurent S. Early and Supernormal Vascular Aging. 2020;76(5):1616–24. https://doi.org/10.1161/hypertensionaha.120.14971

Kohn JC, Lampi MC, Reinhart‐King CA. Age-related vascular stiffening: causes and consequences. Frontiers in Genetics. 2015;06. https://doi.org/10.3389/fgene.2015.00112

Badaras I, Laučytė-Cibulskienė A. Vascular aging and COVID-19. Angiology. SAGE Publications Inc. 2022. https://doi.org/10.1177/00033197221121007

PDDikti - Pangkalan Data Pendidikan Tinggi. 2020. Pddikti.kemdikbud.go.id. https://pddikti.kemdikbud.go.id/asset/data/publikasi/Statistik%20Pendidikan%20Tinggi%202020.pdf

Wang Z, Li W, Liu W, Tian J. Gender is a determinant of carotid artery stiffness independent of age and blood pressure. British Journal of Radiology. 2021;94(1119): 20200796–20200796. https://doi.org/10.1259/bjr.20200796

Sacre JW, Jennings G, Kingwell BA. Exercise and dietary influences on arterial stiffness in cardiometabolic disease. 2014;63(5):888–93. https://doi.org/10.1161/hypertensionaha.113.02277

Stanek A, Bogna Grygiel-Górniak, Klaudia Brożyna-Tkaczyk, Wojciech Myśliński, Cholewka A, Samaneh Zolghadri. The influence of dietary interventions on arterial stiffness in overweight and obese subjects. Nutrients. 2023;15(6):1440–43. https://doi.org/10.3390/nu15061440

Stanek A, Grygiel-Górniak B, Brożyna-Tkaczyk K, Myśliński W, Cholewka A, Zolghadri S. The influence of dietary interventions on arterial stiffness in overweight and obese subjects. Nutrients. 2023;15(6), 1440. https://doi.org/10.3390/nu15061440

Farshidfar F, Koleini N, Ardehali H. Cardiovascular complications of COVID-19. JCI insight. 2021;6:13. American Society for Clinical Investigation. https://doi.org/10.1172/jci.insight.148980

Ganong WF. Buku ajar fisiologi kedokteran. 24th Edition. Jakarta: EGC; 2015.

Araújo CR, da S, Fernandes J, Caetano DS, et al. Endothelial function, arterial stiffness and heart rate variability of patients with cardiovascular diseases hospitalized due to COVID-19. Heart and Lung. 2023;58:210–6. https://doi.org/10.1016/j.hrtlng.2022.12.016

Kar M. Vascular dysfunction and its cardiovascular consequences during and after COVID-19 infection: A narrative review. Vascular Health and Risk Management. 2022;18:105–12. https://doi.org/10.2147/vhrm.s355410

Stanek A, Bogna Grygiel-Górniak, Klaudia Brożyna-Tkaczyk, Wojciech Myśliński, Cholewka A, Samaneh Zolghadri. The influence of dietary interventions on arterial stiffness in overweight and obese subjects. Nutrients. 2023;15(6):1440. https://doi.org/10.3390/nu15061440

Saz‐Lara A, Iván Cavero‐Redondo, Álvarez‐Bueno, C, et al. What type of physical exercise should be recommended for improving arterial stiffness on adult population? A network meta-analysis. European Journal of Cardiovascular Nursing. 2021;20(7):696–716. https://doi.org/10.1093/eurjcn/zvab022

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Published

2024-10-25

How to Cite

Putri, T. Z., Bustamam, N., Faranita, T., & Irmarahayu, A. (2024). The Relationship Between COVID-19 History and Arterial Vascular Elasticity Measured Using Accelerated Photoplethysmograph Analyzer in Medical Students. Acta Medica Indonesiana, 56(3), 322. Retrieved from https://www.actamedindones.org/index.php/ijim/article/view/2677

Issue

Vol. 56 No. 3 (2024): Acta Medica Indonesiana

Section

ORIGINAL ARTICLE

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