Effectiveness of Renal Denervation for Treatment of Resistant Hypertension: an Evidence-based Case Report

Authors

  • Minarma Siagian Department of Physiology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
  • Aldo Ferly Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
  • Arinna Irianti Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
  • Arky Kurniati Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
  • Florence Low Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
  • Ras A. Riza Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia

Abstract

Aim: to determine whether the renal sympathetic – nerve ablation method is more effective compared to multiple anti – hypertensive drug among patients with resistant hypertension. Methods: a search was conducted on PubMed. The selection of title and abstract was conducted using inclusion and exclusion criteria, which led to five relevant articles. The selected studies were critically appraised for its validity, importance and applicability. Results: one of studies showed that renal denervation is not effectively reduced blood pressure in patients with resistant hypertension; nevertheless other studies showed significant results. Conclusion: literature with strongest evidence showed that there is no relationship between renal sympathetic-nerve ablation procedure and reduction of blood pressure. However, as there is still some methodological flaw on the literature, we recommend doing another study that may find the appropriate results. Key words: renal denervation, resistant hypertension.

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Published

2014-10-01

How to Cite

Siagian, M., Ferly, A., Irianti, A., Kurniati, A., Low, F., & Riza, R. A. (2014). Effectiveness of Renal Denervation for Treatment of Resistant Hypertension: an Evidence-based Case Report. Acta Medica Indonesiana, 46(4). Retrieved from https://www.actamedindones.org/index.php/ijim/article/view/111

Issue

Vol. 46 No. 4 (2014)

Section

SPECIAL ARTICLE

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