Correlation Between High-sensitivity C Reactive Protein and Local Arterial Stiffness Measured by Radio Frequency Echotracking System in Type 2 Diabetic Patients

Authors

  • Azri Nurizal Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • Dono Antono Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • Ika P Wijaya Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • Hamzah Shatri Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia

Abstract

Aim: to identify the correlation between hsCRP and arterial stiffness in type-2 diabetic patients. Methods: a cross-sectional study was conducted to assess the plasma levels of hsCRP and carotid arterial stiffness in 40 patients with type-2 diabetes mellitus. The common carotid artery stiffness was evaluated using radio frequency echo-tracking system to determine the local carotid pulse wave velocity (carotid-PWV). Results: median value of hsCRP in this study was 4.5 (0.2 to 18.9) mg/L and the average value of local carotid stiffness was 8.8±1.7 m/sec. High sensitive CRP showed a strong correlation with carotid-PWV (r=0.503, P=0.001). hsCRP level was independently associated with carotid-PWV after adjustment for age, body mass index, and mean arterial pressure (r=0.450, P=0.005). Conclusion: hs-CRP has moderate positive correlation with arterial stiffness in patients with type-2 diabets mellitus. Key words: arterial stiffness, C-reactive protein

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Published

2014-10-01

How to Cite

Nurizal, A., Antono, D., Wijaya, I. P., & Shatri, H. (2014). Correlation Between High-sensitivity C Reactive Protein and Local Arterial Stiffness Measured by Radio Frequency Echotracking System in Type 2 Diabetic Patients. Acta Medica Indonesiana, 46(4). Retrieved from https://www.actamedindones.org/index.php/ijim/article/view/104

Issue

Vol. 46 No. 4 (2014)

Section

ORIGINAL ARTICLE

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