Survival Rate of Cervical Cancer in National Referral Hospital in 2012 - 2014

Laila Nuranna, Aziz Fahrudin

Abstract


Background: cervical cancer is the third leading cause of female deaths worldwide, and it is the leading cause of female deaths in developing countries. A routine survival evaluation is required to imply the result of the treatment. The aim of this study was to determine the cervical cancer patient survival rate at the Cipto Mangunkusumo hospital as national referral hospital in Indonesia. Methods: our retrospective cohort study utilized the medical records of cervical cancer patients from 2012 to 2014 using total population sampling method. The data analysis was conducted using the Kaplan-Meier curve, log rank test and Cox regression to determine significant associations between variables. Results: there were 1,303 subjects with overall survival rates of cervical cancer up to the fifth year of 76%, 65%, 59%, 43% and 34%, respectively, with a median survival of 1,316 days. There were significant differences of hazard ratio for cancer stage variables (p<0.001), and the Cox regression analysis showed that the factor affecting survival was  cancer stage. Conclusion: the 5-year cervical cancer survival rate at the Cipto Mangunkusumo hospital from 2012 to 2014 was 34%.


Keywords


cervical cancer; survival rate; national hospital

References


Globocan Data Sheet. World. 2008;(9856):1-8.

American Cancer Society. Cancer Facts Figures. 2011;1(1):1-68.

Aziz MF. Gynecological cancer in Indonesia. J Gynecol Oncol. 2009;20(1):8-10.

Sirait AM, Soetiarto F, Oemiati R. Kesintasan rate of cervical cancer patients in Dharmais Cancer Hospital. Buletin Penelitian Kesehatan. 2003;31(1):13-24.

Andrae B, Andersson TM, Lambert PC, et al. Screening and cervical cancer cure: population based cohort study. Brit Med J. 2012;344:e900.

Kari J, Syrjänen SC. Histological and quantitative pathological prognostic factors in cervical cancer. CME J Gynecol Oncol. 2001;6:279-301.

Vistad I, Fossa SD, Dahl AA. A critical review of patient-rated quality of life studies of long-term survivors of cervical cancer. Gynecol Oncol. 2006;102(3):563-72.

Nuranna L, Prastasari R. Kesintasan pasien kanker serviks tahun 2005/2006 di RS Cipto Mangunkusomo (Survival Rate of Cervical Cancer Patients in 2005/2006 at Cipto Mangunkusomo Hospital). Universitas Indonesia, 2012.

Sirait AM, Ariawan I, Aziz MF. Ketahanan hidup penderita kanker serviks di Rumah Sakit Dr Cipto Mangunkusumo Jakarta (Survival Rate of Cervical Cancer Patients at Cipto Mangunkusumo Hospital Jakarta). Majalah Obstetrik Ginekologi Indonesia. 1997;21:182-190.

USA Surveillance Epidemiology. Stat fact sheets: cervix uteri cancer 2016. Retrieved from: http://seer.cancer.gov/statfacts/html/cervix.html on 17 December 2017

Shingleton HM, Maria CB, Fremgen A, et al. Is there really a difference in survival of women with squamous cell carcinoma, adenocarcinoma and adenosquamous cell carcinoma of the cervix? Cancer. 1995;76:1948-55.


Full Text: PDF

Refbacks

  • There are currently no refbacks.


Copyright (c) 2019 Acta Medica Indonesiana