Acute Appendicitis in a Patient with Systemic Lupus Erythematosus

Hendra Gunawan, Awalia Awalia, Joewono Soeroso

Abstract


Systemic lupus erythematosus (SLE) is a chronic excacerbative autoimmune disease with wide clinical spectrum. Gastrointestinal manifestasion is a frequent clinical manifestasion seen in SLE. Management with glucocorticoid and non-steroid anti-inflammatory drugs (NSAID) can mask the gastrointestinal symptoms in patient with SLE. One of the etiologies of gastrointestinal manifestations in SLE is acute appendicitis. Patients with acute appendicitis usually have abdominal pain as its chief complaint. The pathophysiology of acute appendicitis can occur primarily from SLE and secondary from other causes eg: infection, inflammation, etc. When a SLE patient has acute appendicitis as its initial assessment, determining its etiology is pivotal to give comprehensive management and preventing life-threatening complications.


Keywords


systemic lupus erythematosus (SLE); acute appendicitis; abdominal pain

References


Merrill JT, Buyon JP, Utset T. A 2014 update on the management of patients with systemic lupus erythematosus. Seminars in Arthritis and Rheumatism. 2014;44(2):e1-e2.

Tian X-P, Zhang X. Gastrointestinal involvement in systemic lupus erythematosus: Insight into pathogenesis, diagnosis and treatment. World J Gastroenterol. 2010;16(24):2971-7.

Daruwala C, Mercogliano G, Harder TP. Gastrointestinal manifestasions of systemic lupus erythematosus and scleroderma. Clin Med: Gastroenterol. 2009;2:7-12.

Cellini C, Hoda SA, Spigland N. Lupus-associated vasculitis manifesting as acute appendicitis in a 16 year old girl. Pediatric Rheumatol. 2008;6(10):1-3.

Al-Hakeem MS, McMillen MA. Evaluation of abdominal pain in systemic lupus erythematosus. American J Surg. 1998;176(1):291-4.

Yuan S, Lian F, Chen D, et al. Clinical features and associated factors of abdominal pain in systemic lupus erythematosus. J Rheumatol. 2013;40(12):2015-22.

Sultan SM, Ioannou Y, Isenberg D. A review of gastrointestinal manifestations of systemic lupus erythematosus. Rheumatol. 1999;38(2):917-32.

Parks NA, Schroeppel TJ. Update on imaging for acute appendicitis. Surg Clin North Am. 2011;91(1):141-54.

Anoosh. F, Shariff R, Ambujakshan D, et al. Acute abdomen as initial presentation in a patient with systemic lupus erythematosus. Am J Case Rep. 2009;10(3):55-8.

Carr NJ. The pathology of acute appendicitis. Annals Diag Pathol. 2000;4(1):46-58.

Indonesia Rheumatology Association. Diagnosis dan pengelolaan lupus eritematosus sistemik. 1st edition. Jakarta: Indonesia Rheumatology Assoc; 2011. p. 17.

Solomkin JS, Mazuski JE, Rodvold KA, et al. Diagnosis and management of complicated intra-abdominal infection in adults and children: Guidelines by the surgical infection society and the infectious diseases society of America. Clin Infect Dis. 2008;50(4):133-64.


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