Unusual Co-existence of Drug-Susceptible Lung Tuberculosis and Drug-Resistant Pleural Tuberculosis: A Rare Case Presentation of Dual Infection

Authors

  • Herikurniawan Herikurniawan Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Joanna Audrey Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Mira Yulianti Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Ni Nyoman Indira Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Cleopas Martin Rumende Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Keywords:

drug-susceptible tuberculosis, drug-resistant tuberculosis, extrapulmonary tuberculosis, pulmonary tuberculosis, dual infection

Abstract

Tuberculosis (TB) has become one of the global burdens of disease, with increasing morbidity and mortality every year. Tuberculosis can affect not only the lungs but also the extrapulmonary organs. The prevalence of drug-resistant tuberculosis (DR-TB) is rising and has caused a higher mortality rate than drug-susceptible tuberculosis (DS-TB). This article presents a patient with a rare co-infection of pulmonary DS-TB and pleural DR-TB. Pulmonary and pleural TB (pTB) was diagnosed using the Xpert MTB/RIF assay. The patient was treated with an individualized DR-TB regimen and recovered.

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Published

2025-07-08

How to Cite

Herikurniawan, H., Audrey, J., Yulianti, M., Indira, N. N., & Rumende, C. M. (2025). Unusual Co-existence of Drug-Susceptible Lung Tuberculosis and Drug-Resistant Pleural Tuberculosis: A Rare Case Presentation of Dual Infection. Acta Medica Indonesiana, 57(2), 237. Retrieved from http://www.actamedindones.org/index.php/ijim/article/view/2509