HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study

Authors

  • Elsayed Abed Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, Egypt
  • Ahmed Farag El-adawey Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, Egypt
  • Mohamed Hamed Rashad Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, Egypt
  • Ahmed Essmat Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, Egypt
  • Mohammed Ali Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, Egypt
  • Ahmed Hassan Elsheshiny Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, Egypt
  • Abdel-Ghaffar Fayed Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, Egypt
  • Fathy Elbaz Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, Egypt
  • Mahmoud Galal Ahmed Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, Egypt
  • Zohreh Abna MS Fellowship, Department of Neurology, Tehran University of Medical Sciences, Tehran, Iran
  • Shaimaa Sayed Khater Department of Neurology, Faculty of Medicine, Ain Shams University, Cairo, 11566, Egypt

Keywords:

Progressive multifocal, leukoencephalopathy, JC virus, demyelinating disease

Abstract

Progressive multifocal leukoencephalopathy (PML) is a rare, life-threatening, infectious, lytic, demyelinating disease that results from reactivation of the virulent JC polyomavirus (JCV) “major opportunistic infection” in immunosuppressed individuals. We reported a case of a young girl who presented with new onset focal neurological defect, evaluated, and laboratory and radiological findings in the context of a clinical setting confirmed HIV-related-PML infection. However, remyelination does not occur, the patients may develop complications in the long term including cognitive impairment, sensory deficits, motor deficits, and disturbances in balance. We must increase our knowledge about HIV- related PML in any patient with reduced immunity and who presented with new onset neurological defect. 

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Published

2023-07-28

How to Cite

Abed, E., El-adawey, A. F., Rashad, M. H., Essmat, A., Ali, M., Elsheshiny, A. H., Fayed, A.-G., Elbaz, F., Ahmed, M. G., Abna, Z., & Khater, S. S. (2023). HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study. Acta Medica Indonesiana, 55(2), 211. Retrieved from http://www.actamedindones.org/index.php/ijim/article/view/2336

Issue

Vol. 55 No. 2 (2023): Acta Medica Indonesiana

Section

CASE REPORT

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